Active ingredient

Chlorothalonil

Description

Chlorothalonil is a highly effective active ingredient belonging to the nitrile chemical class. In agricultural practice, it is widely used as a broad-spectrum fungicide. Due to its unique properties, it has become an essential component in protection programs for vegetable, cereal, and fruit crops against a wide range of pathogenic microorganisms.

The primary mode of action of chlorothalonil involves inhibiting the enzymatic activity within fungal cells. The substance binds to glutathione and other thiol-containing compounds in the fungus, leading to irreversible disruption of cellular respiration and cessation of pathogen growth. It acts exclusively as a contact fungicide, meaning it does not penetrate the plant but instead creates a protective barrier on the surface of leaves and stems.

The preparation demonstrates high efficacy against a broad range of phytopathogens, including downy mildew, late blight, septoria, anthracnose, and various types of leaf spots. It is applied to crops such as potatoes, tomatoes, cucumbers, onions, and cereal grains during the active growth period to prevent infections.

Specific usage of chlorothalonil requires strict adherence to technical guidelines. Because the preparation lacks systemic properties, it is crucial to ensure thorough and uniform coverage of the plant surface with the spray solution. In agronomy, it is often utilized in tank mixtures with systemic fungicides to prevent the development of pathogen resistance.

  • Long-lasting protective effect in the absence of rain.
  • Good rainfastness when used with appropriate adjuvants.
  • No phytotoxicity for most commercially grown crops.
  • Highly effective against a broad spectrum of Ascomycetes and Deuteromycetes.

Safety precautions when handling chlorothalonil include the mandatory use of personal protective equipment for respiratory protection, skin, and eyes. The substance is moderately toxic to mammals; however, it requires careful handling near water bodies due to its high toxicity to fish and aquatic organisms. It is recommended to strictly observe pre-harvest intervals.

Regulatory

Status in the European Union

Not approved in the EU

CAS number
1897-45-6
Category (EU)
FU - Fungicide
Approved from
01.03.2006
Approval until
20.05.2019
ADI
0.015 mg/kg bw/day
ARfD
0.05 mg/kg bw
AOEL
0.003 mg/kg bw/day
Hazard classification (CLP)
Acute Tox. 2 - H330Aquatic Acute 1 - H400Aquatic Chronic 1 - H410Carc. 2 - H351Eye Dam. 1 - H318STOT SE 3 - H335Skin Sens. 1 - H317
EU legislation

Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.

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