Famoxadone
Description
Famoxadone is a potent active ingredient belonging to the oxazolidinedione chemical class. It is widely utilized in professional agriculture as a contact fungicide, primarily designed to combat a range of fungal pathogens, specifically those belonging to the class of oomycetes which cause significant crop damage.
The mechanism of action of famoxadone involves the inhibition of mitochondrial respiration in the target fungi. By blocking electron transport at the q0-center of the cytochrome b/c1 complex, the fungicide effectively cuts off the energy supply to the pathogen's cells, preventing spore germination and the development of mycelium.
This substance is commonly applied to protect high-value crops such as potatoes, tomatoes, and grapes. It is particularly effective in controlling late blight and downy mildew. Because of its specific mode of action, it is frequently formulated in mixture with other fungicides to enhance the spectrum of activity and prevent the development of resistant strains.
Key application features include the compound's unique ability to bind to the plant's waxy leaf cuticle. This trait provides excellent resistance to wash-off by rain, which ensures extended residual protection. This long-lasting effect is crucial for farmers looking to maintain crop health during periods of humid or unpredictable weather.
Safety precautions when handling famoxadone are essential. Applicators should wear appropriate personal protective equipment (PPE) and strictly follow the recommended application rates to minimize environmental impact. It is also important to adhere to the designated pre-harvest intervals to ensure that the food products are free from chemical residues.
Status in the European Union
Not approved in the EU
- CAS number
- 131807-57-3
- Category (EU)
- FU - Fungicide
- Approved from
- 01.10.2002
- Approval until
- 09.09.2021
- ADI
- 0.006 mg/kg bw/day
- ARfD
- 0.1 mg/kg bw
- AOEL
- 0.0024 mg/kg bw/day
Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.