Active ingredient

Flumioxazin

Description

Flumioxazin is a potent active ingredient belonging to the N-phenylphthalimide chemical class. In modern agriculture, it is widely utilized as a highly effective, broad-spectrum herbicide designed to control a variety of broadleaf weeds and some grasses in several field crops.

The mode of action of flumioxazin involves the inhibition of the protoporphyrinogen oxidase (PPO) enzyme. By blocking this enzyme, the chemical causes a buildup of porphyrins in plant tissues, which, upon exposure to sunlight, triggers a rapid breakdown of cell membranes. This leads to the quick desiccation and death of the target weeds shortly after germination or emergence.

Flumioxazin is primarily applied as a soil-active herbicide in crops such as soybeans, corn, peanuts, and vineyards. It is particularly valued for its effectiveness against stubborn species such as pigweed, lambsquarters, and ragweed. By forming a residual barrier in the soil, it provides extended control, suppressing subsequent flushes of weed growth throughout the season.

Application strategies must account for environmental conditions to ensure optimal performance. Soil moisture is critical for the activation of the herbicidal barrier, and uniform coverage is essential for the best results. Agronomists typically advise careful consideration of soil organic matter content and crop stage to avoid potential phytotoxicity and to optimize the herbicide's selectivity.

Safety precautions are essential when handling flumioxazin. Users must wear appropriate personal protective equipment (PPE) to minimize exposure through skin contact or inhalation. Furthermore, it is crucial to follow label guidelines to prevent spray drift into non-target areas and to ensure environmental safety, particularly near water bodies and protected wildlife habitats.

Regulatory

Status in the European Union

Approved in the EU

CAS number
103361-09-7
Approved from
01.03.2022
Approval until
28.02.2037
ADI
0.018 mg/kg bw/day
ARfD
0.03 mg/kg bw
AOEL
0.022 mg/kg bw/day
Hazard classification (CLP)
Aquatic Acute 1 - ---Aquatic Chronic 1 - H410Repr. 2 - H361d

Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.

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