Active ingredient

Flusilazole

Description

Flusilazole is a potent systemic fungicide belonging to the triazole chemical class. It is widely recognized in professional agricultural practices for its broad-spectrum activity against various pathogenic fungi. The compound acts as a powerful curative and preventive agent, making it a staple in integrated pest management programs for both cereal and high-value horticultural crops.

The mechanism of action involves the inhibition of ergosterol biosynthesis within the fungal cells. Specifically, flusilazole targets the enzyme 14-alpha-demethylase, which is critical for membrane integrity in fungi. By disrupting this process, the substance effectively starves the fungus, inhibits mycelial growth, and stops the sporulation process, ultimately leading to the eradication of the infection.

Flusilazole is utilized across a diverse range of crops including wheat, barley, maize, oilseed rape, sugar beet, and grapes. It demonstrates high efficacy against major agricultural threats such as powdery mildew, leaf rust, Septoria leaf blotch, and various types of leaf spots. Its ability to provide long-lasting control makes it highly valuable during periods of peak infection pressure.

Regarding application, growers should focus on the timing of treatments to coincide with the early stages of disease development. Because flusilazole has systemic properties, it is absorbed rapidly by the plant tissues and translocated, which provides protection to new growth. However, to maintain high levels of efficacy and prevent the development of resistant fungal strains, it is standard practice to rotate flusilazole with fungicides possessing different modes of action.

Safety precautions are mandatory when handling flusilazole to ensure user and environmental protection. Operators must wear appropriate personal protective equipment (PPE) to prevent skin and eye contact. Furthermore, because the substance poses potential risks to aquatic life, all applications must strictly follow buffer zone requirements, and disposal of containers or equipment washings must comply with local environmental regulations.

Regulatory

Status in the European Union

Not approved in the EU

CAS number
85509-19-9
Category (EU)
FU - Fungicide
ADI
0.002 mg/kg bw/day
ARfD
0.005 mg/kg bw
AOEL
0.005 mg/kg bw/day
Hazard classification (CLP)
Acute Tox. 4 - H302Aquatic Chronic 2 - H411Carc. 2 - H351Repr. 1B - H360D
EU legislation

Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.

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