Isoxaflutole
Description
Isoxaflutole is a highly active herbicide belonging to the isoxazole chemical class. It is primarily used for the selective control of a broad spectrum of annual broad-leaved weeds and certain grasses in maize crops. Its reliability and systemic uptake make it a preferred choice for professional agronomic programs focused on high-yield production.
The herbicidal action involves the inhibition of the 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) enzyme. This disruption halts the synthesis of carotenoids, which are essential for protecting chlorophyll from photo-oxidation. Consequently, sensitive weeds exhibit characteristic bleaching (whitening) of the leaves and shoot tissue, which is quickly followed by plant necrosis and death.
Isoxaflutole is used exclusively on corn, where it can be applied pre-emergence. It is particularly effective against tough weed species such as common lambsquarters, pigweed, and various smartweed species. By incorporating this active ingredient into a herbicide program, growers can significantly reduce weed competition during the critical early growth stages of the corn crop.
A distinctive feature of isoxaflutole is its unique reactivation property. The compound remains stable in the soil until triggered by rainfall, at which point it activates to control emerging weed flushes. This biological buffer provides consistent and long-lasting weed suppression, even in regions with variable or unpredictable early-season moisture levels.
Proper application guidelines must be followed to maximize efficacy and minimize environmental impact. Farmers should ensure precise nozzle calibration and avoid drift onto non-target vegetation. Always consult local regulations for maximum application rates and re-entry intervals. Protective equipment must be worn during handling to ensure operator safety.
Status in the European Union
Approved in the EU
- CAS number
- 141112-29-0
- Approved from
- 01.08.2019
- Approval until
- 31.07.2034
- ADI
- 0.02 mg/kg bw/day
- ARfD
- 0.05 mg/kg bw
- AOEL
- 0.012 mg/kg bw/day
Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.