Active ingredient Especially harmful

Carbosulfan

Description

Carbosulfan is a broad-spectrum, systemic insecticide and nematicide belonging to the carbamate chemical class. It is widely utilized in professional agriculture to control a diverse range of pests that threaten crop productivity. Its formulation allows for both contact and stomach action, making it a versatile tool in integrated pest management programs.

The biological mechanism of carbosulfan involves the inhibition of the enzyme acetylcholinesterase within the nervous system of insects. This interference prevents the normal breakdown of neurotransmitters, leading to the accumulation of acetylcholine, causing paralysis and rapid death of the targeted pests. In vivo, the molecule is metabolized into its active form, carbofuran, which sustains the insecticidal effect.

This active ingredient is typically applied to various crops including corn, sugar beets, potatoes, and vegetable plants. It is particularly effective against soil-dwelling insects like wireworms, as well as sap-sucking pests like aphids and thrips. Application methods often include soil incorporation during planting or the treatment of seeds to protect crops from early-season damage.

A key operational advantage of carbosulfan is its systemic nature, which allows the plant to absorb the active ingredient through its roots and transport it to foliage. This internal protection helps mitigate the impact of pests that feed on plant tissues. The duration of protection is influenced by environmental factors such as soil moisture, temperature, and microbial activity, which affect the degradation rate of the compound.

Given its high toxicity, stringent safety protocols must be followed during application. Operators are required to use full personal protective equipment to prevent exposure. Furthermore, because carbosulfan is highly toxic to aquatic organisms, beneficial insects, and pollinators, it must be used with caution, avoiding application near water bodies or during periods of bee activity to minimize environmental impact.

Regulatory

Status in the European Union

Not approved in the EU

CAS number
55285-14-8
Category (EU)
NE - Nematicide
ADI
0.005 mg/kg bw/day
ARfD
0.005 mg/kg bw
AOEL
0.005 mg/kg bw/day
Hazard classification (CLP)
Acute Tox. 2 - H330Acute Tox. 3 - H301Aquatic Acute 1 - H400Aquatic Chronic 1 - H410Skin Sens. 1 - H317
EU legislation

Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.

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