Active ingredient

Mandestrobin

Description

Mandestrobin is a high-performance active ingredient categorized within the strobilurin chemical class. It is widely employed in modern agriculture as a systemic fungicide, playing a critical role in disease management strategies for various essential crops by targeting diverse fungal pathogens.

The primary mechanism of action involves the inhibition of mitochondrial respiration in target fungi. By binding to the QO-site of complex III in the respiratory chain, mandestrobin effectively halts electron transport. This disruption prevents ATP production, causing the rapid cessation of fungal growth and the eventual death of the pathogen.

Mandestrobin is utilized on a variety of crops, including cereals, soybeans, and horticultural products. It provides excellent control against a broad range of diseases such as powdery mildew, leaf spot diseases, rusts, and anthracnose. Its systemic nature allows it to move within the plant, providing both protective and curative benefits.

For optimal field performance, it is recommended to apply mandestrobin at the earliest stages of disease pressure. While the compound is highly effective, agricultural best practices dictate that it should be used in rotation with fungicides from different chemical families to mitigate the risk of pathogen resistance and ensure long-term efficacy.

Safety precautions are essential when handling mandestrobin. Operators should always wear appropriate personal protective equipment (PPE), including gloves and respiratory protection, to prevent accidental exposure. Furthermore, users must strictly adhere to label instructions regarding buffer zones, water safety, and pre-harvest intervals to ensure safety for both the applicator and the consumer.

Regulatory

Status in the European Union

Approved in the EU

CAS number
173662-97-0
Approved from
09.12.2015
Approval until
09.06.2029
ADI
0.19 mg/kg bw/day
ARfD
Not appl.
AOEL
0.19 mg/kg bw/day

Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.

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