Pyrimethanil
Description
Pyrimethanil is a potent systemic fungicide belonging to the anilinopyrimidine chemical class. It is widely employed in modern agriculture to protect a variety of crops from fungal pathogens, primarily those belonging to the Ascomycota and Deuteromycota phyla. Its unique ability to redistribute within plant tissues ensures that even parts of the plant not directly covered during spraying receive adequate protection.
The mode of action of pyrimethanil involves the inhibition of the secretion of fungal hydrolytic enzymes. By preventing the fungus from secreting these essential enzymes, the compound effectively disrupts the pathogen's ability to infect plant tissues and form lesions. This biochemical interruption is highly specific, which allows for effective control even of fungal strains that have developed resistance to other common fungicide groups.
The primary use of pyrimethanil is in horticulture and viticulture, particularly for controlling gray mold (Botrytis cinerea) and apple or pear scab. Due to its efficacy at lower temperatures, it is a preferred choice for early-season treatments in orchards when other contact fungicides remain ineffective. Its wide spectrum of activity makes it an essential tool for integrated pest management programs.
A distinctive feature of pyrimethanil is its vapor phase activity, which allows the active ingredient to penetrate dense plant canopies or tight fruit clusters that are often missed by conventional droplet-based application. This volatile nature ensures a more uniform coverage, although it requires careful timing to avoid application under conditions of excessive wind or extreme heat that might cause premature degradation of the protective film.
Regarding safety, pyrimethanil is classified as a moderately hazardous substance, necessitating strict adherence to protective guidelines. Applicators should always wear appropriate personal protective equipment, including gloves and respirators. Precautions must be taken to prevent drift into non-target areas and water sources, as the compound can be harmful to aquatic life if exposed in high concentrations during accidental spills or runoff.
Status in the European Union
Approved in the EU
- CAS number
- 53112-28-0
- Approved from
- 01.05.2026
- Approval until
- 30.04.2041
- ADI
- 0.013 mg/kg bw/day
- ARfD
- 1.0 mg/kg bw
- AOEL
- 0.3 mg/kg bw/day
Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.