Active ingredient

Spiroxamine

Description

Spiroxamine is a potent active ingredient belonging to the spiroketalamine chemical class. It is widely employed in modern agriculture as a systemic fungicide designed to manage a broad range of fungal pathogens, providing robust protection for various staple crops and specialized horticultural plants.

The mechanism of action of spiroxamine involves the inhibition of ergosterol biosynthesis within fungal cells. By targeting specific enzymes responsible for demethylation and isomerization, the substance disrupts the integrity of fungal cell membranes. This process effectively halts mycelial growth and inhibits spore production, offering both curative and preventive benefits.

This active substance is most frequently utilized in the cultivation of cereals, such as wheat and barley, as well as in viticulture. It is highly regarded for its efficacy against powdery mildew, various rust diseases, and leaf spot pathogens. Due to its systemic movement, it can translocate within the plant tissue to protect new growth from infection.

Agronomists often integrate spiroxamine into spray programs, often in tank mixes with other fungicides to broaden the control spectrum and manage resistance effectively. Its high lipophilicity ensures rapid absorption into the leaf cuticle, which provides excellent rain-fastness shortly after application, making it a reliable tool under volatile weather conditions.

  • Rapid systemic penetration
  • Excellent control of powdery mildew
  • Superior rain-fastness
  • Ideal partner for resistance management

Handling spiroxamine requires adherence to strict safety protocols to ensure human and environmental health. Operators must wear appropriate protective clothing and respiratory gear during application. Furthermore, it is critical to prevent product runoff into aquatic environments, as it poses risks to fish and other aquatic invertebrates. Always store the product according to label instructions to maintain stability and prevent accidental exposure.

Regulatory

Status in the European Union

Approved in the EU

CAS number
118134-30-8
Approved from
01.01.2012
Approval until
30.11.2029
ADI
0.025 mg/kg bw/day
ARfD
0.1 mg/kg bw
AOEL
0.015 mg/kg bw/day
Hazard classification (CLP)
Acute Tox. 4 - H302Acute Tox. 4 - H312Acute Tox. 4 - H332Aquatic Acute 1 - H400Aquatic Chronic 1 - H410Repr. 2 - H361dSTOT RE 2 - H373Skin Irrit. 2 - H315Skin Sens. 1 - H317

Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.

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