Active ingredient

Zoxamide

Description

Zoxamide is a powerful active ingredient belonging to the benzamide chemical class, widely used as a specialized fungicide. It is specifically designed to combat pathogens classified as oomycetes, which are responsible for some of the most devastating agricultural diseases. Its localized systemic action makes it a reliable choice for professional plant protection.

The mechanism of action of Zoxamide is centered on inhibiting the mitosis process in fungal cells. By binding to beta-tubulin, the substance prevents the formation of microtubules, which are essential for cell division and structural integrity. This mechanism effectively arrests the development of the pathogen, preventing the germination of spores and further colonization of host tissues.

Zoxamide is primarily employed to protect potato crops against late blight (Phytophthora infestans) and vineyards against downy mildew (Plasmopara viticola). Due to its broad-spectrum efficacy, it is also effective against various species of Alternaria. Its ability to provide both preventative and curative control makes it a cornerstone of modern disease management programs.

Key application features include high rainfastness, as the compound rapidly adsorbs into the waxy layer of the leaves. This persistence ensures long-lasting protection even under challenging weather conditions. To manage resistance, agronomists often include Zoxamide in rotation schedules, utilizing its unique mode of action to lower the risk of pathogens developing insensitivity to fungicides.

When handling products containing Zoxamide, it is mandatory to follow strict safety protocols, including the use of appropriate personal protective equipment (PPE) such as gloves, goggles, and respirators. Users must ensure that the substance does not contaminate water sources. Proper storage in a cool, ventilated, and secured area is essential to maintain the chemical integrity and ensure safety on the farm.

Regulatory

Status in the European Union

Approved in the EU

CAS number
156052-68-5
Approved from
01.07.2018
Approval until
30.06.2033
ADI
0.5 mg/kg bw/day
ARfD
Not appl.
AOEL
0.3 mg/kg bw/day
Hazard classification (CLP)
Aquatic Acute 1 - H400Aquatic Chronic 1 - H410Skin Sens. 1 - H317

Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.

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