Active ingredient

Mefentrifluconazole

Description

Mefentrifluconazole belongs to the chemical class of triazoles, specifically the isopropanol-azole subgroup. It is a cutting-edge active ingredient known for its superior biological performance, providing high efficacy against a wide range of fungal pathogens, even under challenging environmental conditions where traditional triazoles often fail.

The mode of action involves the inhibition of the C14-demethylase enzyme, which is essential for the biosynthesis of ergosterol in fungal cell membranes. The unique molecular structure of mefentrifluconazole allows it to bind tightly to the target enzyme, effectively controlling fungi even in strains that have developed resistance to earlier generation fungicides.

This substance is primarily used as a fungicide for various crops, including cereals (wheat, barley), corn, soybeans, pome fruits, and grapes. It targets major diseases such as Septoria leaf blotch, various types of rust, powdery mildew, and tan spot, providing both preventative and curative control to protect crop yield potential.

A key feature of mefentrifluconazole is its excellent systemic movement within the plant and high lipophilicity. It quickly penetrates the waxy leaf cuticle and forms reservoirs within the leaf tissue, allowing for a long-lasting protective effect against fungal infections while maintaining stability against rainfall wash-off.

Safe handling practices are mandatory when using products containing mefentrifluconazole. Operators must wear appropriate personal protective equipment, including gloves and respirators. Always follow the specific label instructions regarding dosage, application timing, and pre-harvest intervals to ensure environmental safety and produce quality.

Regulatory

Status in the European Union

Approved in the EU

CAS number
1417782-03-6
Approved from
20.03.2019
Approval until
20.03.2029
ADI
0.035 mg/kg bw/day
ARfD
0.15 mg/kg bw
AOEL
0.035 mg/kg bw/day
EU legislation

Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.

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