Description
Metalaxyl is a potent active ingredient belonging to the phenylamide (acylalanine) chemical class. It is widely recognized as a highly effective systemic fungicide used in global agriculture to combat a variety of plant pathogens, specifically those belonging to the Oomycetes class. Its ability to penetrate plant tissues ensures rapid and reliable disease control.
The mode of action of metalaxyl involves the inhibition of ribosomal RNA synthesis in fungal pathogens. By targeting the RNA polymerase enzyme, the fungicide effectively blocks the metabolic processes of the fungus, leading to the rapid cessation of mycelial growth and spore development. Its systemic translocation within the plant allows for upward (acropetal) movement, protecting new vegetative growth from infection.
Metalaxyl is primarily effective against downy mildew, late blight, damping-off, and various root rot diseases. It is extensively used on crops such as potatoes, tomatoes, cucumbers, onions, and various fruit crops. It is also a popular choice for seed treatment, where it protects seedlings from soil-borne pathogens during the critical early stages of crop emergence.
- Seed treatment to prevent soil-borne infections.
- Foliar spraying during high disease pressure periods.
- Usage in combination with protectant fungicides.
- Strategic application to manage resistance.
A significant aspect of using metalaxyl is the management of fungal resistance. Pathogens can develop resistance to phenylamides relatively quickly; therefore, it is strongly advised to limit the number of applications per season and rotate with fungicides that possess different modes of action. Integrated pest management (IPM) practices should always be followed to maintain the product's long-term effectiveness.
Safety is paramount when handling metalaxyl. Operators should use appropriate personal protective equipment (PPE) to prevent skin contact and inhalation. Environmental protection is also critical, particularly in terms of preventing runoff into aquatic systems. Always refer to the specific product label for safety instructions, dosage rates, and pre-harvest intervals to ensure consumer safety.
Status in the European Union
Approved in the EU
- CAS number
- 57837-19-1
- Approved from
- 01.07.2010
- Approval until
- 30.09.2026
- ADI
- 0.08 mg/kg bw/day
- ARfD
- 0.5 mg/kg bw
- AOEL
- 0.08 mg/kg bw/day
Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.
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