Active ingredient

Myclobutanil

Description

Myclobutanil is a potent systemic fungicide belonging to the triazole chemical class. It is widely recognized in professional agriculture for its dual action, offering both preventive and curative properties. Its systemic nature allows the active ingredient to be absorbed by plant tissues and translocated throughout the plant, effectively shielding new growth from fungal infections.

The mode of action for myclobutanil is the inhibition of ergosterol biosynthesis, a vital component of fungal cell membrane integrity. By interfering with the enzyme demethylase, the substance effectively stops the growth of the fungal mycelium and prevents spore germination. This cellular disruption eventually leads to the eradication of the pathogen on the treated plant surfaces.

This compound is primarily used in the management of various diseases such as powdery mildew, scab, rust, and various leaf spots. It is commonly applied to a wide array of crops, including grapes, pome fruits, stone fruits, and ornamental plants. Due to its high efficacy, it serves as a cornerstone in disease management programs, particularly where powdery mildew presents a significant risk to yield quality.

Effective application relies on timing and proper coverage of the plant canopy. Myclobutanil demonstrates good compatibility with many other pesticides in tank mixes, which allows for convenient integrated pest management. However, to maintain its effectiveness, it is recommended to rotate it with fungicides of different modes of action to mitigate the risk of pathogen resistance development.

Safety and handling procedures are essential when working with myclobutanil. Operators must wear appropriate personal protective equipment (PPE), including chemical-resistant gloves and eye protection. It is critical to prevent runoff into water sources and to adhere strictly to the pre-harvest interval (PHI) specified on the product label to ensure that residues remain within safe legal limits.

Regulatory

Status in the European Union

Not approved in the EU

CAS number
88671-89-0
Category (EU)
FU - Fungicide
Approved from
01.06.2011
Approval until
31.05.2021
ADI
0.025 mg/kg bw/day
ARfD
0.31 mg/kg bw
AOEL
0.03 mg/kg bw/day
Hazard classification (CLP)
Acute Tox. 4 - H302Aquatic Chronic 2 - H411Eye Irrit. 2 - H319Repr. 2 - H361d

Regulatory status data: EU Pesticides Database © European Union, CC BY 4.0. EU status is for reference only and does not replace national registration in your country.

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